Targeting joint inflammation for osteoarthritis management through stimulus-sensitive hyaluronic acid based intra-articular hydrogels

Intra-articular hyaluronic acid injections for knee osteoarthritis.

Knee osteoarthritis is a common but often difficult problem to manage in primary care. Traditional nonsurgical management, consisting of lifestyle modification, physical therapy and pharmacologic therapy (e.g., analgesics, anti-inflammatory medications), is often ineffective or leaves residual symptoms. Viscosupplementation is a newly available option for patients with symptomatic knee osteoart...

Updates on intra-articular hyaluronic Acid therapy for knee osteoarthritis.

Intra-articular injection of hyaluronic acid for temporomandibular joint osteoarthritis in elderly patients.

BACKGROUND Preliminary findings gave encouraging results for the use of hyaluronic acid in temporomandibular joints with inflammatory/degenerative processes. This investigation aimed at evaluating retrospectively the efficacy of intra-articular injections of hyaluronic acid in elderly patients (aged >65 years) with osteoarthritis of the temporomandibular joint as compared with those of a group ...

Therapeutic Efficacy of Intra-Articular Hyaluronic Acid in Osteoarthritis Knee

Osteoarthritis (OA) is an increasingly important public health problem [1]. It is slowly progressive, can cause symptoms ranging from mild to disabiling. Osteoarthritis is a common cause of knee pain especially in the elderly. It is characterised by loss of articular cartilage, subchondral sclerosis, joint deterioration and osteophyte formation [1]. The current treatment for knee OA consists of...

Effects of intra-articular hyaluronic acid and corticosteroid therapies on articular cartilage in experimental severe osteoarthritis.